Autism project draws over 100 proposals
Initiative announced by Kennedy to mine data
By: Robin Respaut
Ahmed Aboulenein
and Julie Steenhuysen
Reuters
WASHINGTON - Researchers have submitted more than 100 proposals to participate in the Trump administration's $50 million study into possible causes of autism, with a list of up to 25 grant winners experted to be announced by the end of September, [2025 people with knowledges of the plans told Reuters.
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Health and Human Services Secretary Robert F. Kennedy Jr. announced the Autism Data Science Initiative in May [2025] and put the National Institute of Health in charge of it. the program aims to mine large datasets to investigate possible contributors to autism and evaluate the outcomes of existing treatments.
..... Studies chosen for funding might begin to show results in two to three years, according to the government's request for research proposals.
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The effort is proceeding separately from a review of vaccine safety commissioned by Kennedy, who has long promoted the idea that vaccines contribute to autism, contrary to scientific evidence. he has promised to announce health policy changes in September [2025] "that will dramatically impact the effects" related to autism, without providing details on the data that would support such changes.
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A spokesperson for the Department of Health and Human Services, which oversees NIH, said the agency is committed to addressing the rise in autism and will issue awards in September [2025] "Pending receipt of scientifically meritorious ideas from the research community." They did not comment on any policy changes planed by Kennedy.
..... Proposals for the NIH grant funding involve nearly 500 major universities and research institutions, advocacy organizations, and data firms, according to a list of applicants reviewed by Reuters. Among the prominent names: Harvard University. Columbia University, Brigham and Women's Hospital, Stanford University and Johns Hopkins University.
..... "I know many colleagues who applied for it, because they weren't sure there would be any other finding for autism research anytime soon," said Dr. Helen Tager-Flusberg, directrix of Boston University's Center for Autism Research Excellence, adding they include many of the "most reputable scientists" in the field.
..... In August, [2025] the U.S. Supreme Court allowed the Trump administration proceed with sweeping cuts to NIH research funding, including some projects related to autism. Some of the universities applied to the NIH autism program have separately seen scientific funding cut by the Trump administration over their diversity policies or allegations of antisemitism on campus.
Rise in autism prevalence
..... Kennedy's assertion that the United States is in the grip of an "autism epidemic" fueled by "environmental toxins" has gained momentum as U.S. rates of the disorder have risen dramatically since 2000, to 1 in 31 children
..... Decades of research has not yield firm answers on what contributes to autism, but many scientist believe genetics, potentially in combination with environmental influences, play a role.
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Experts say that autism cannot be deserved as an epidemic and that it may be due to a disruption in fetal development. May say that the rise in autism prevalence is due to an expanded definition of the disorder and increasing awareness and diagnosis.
..... Applicants to the Autism Data Science initiative were asked to describe how they would use datasets to seek clues about the genetic and non-geneitc contributors to autism and to identify patterns associated with interventions and other services provided to people with the condition.
..... "The very large increase in autism prevalence that we've seen over the past 25 years leads to an obvious question: What is behind this increase?" Dr. Cindy Lawler, chief of genes, environment and health branch at the National Institute for Environmental Health Sciences, said during a June [2025] webinar about the new funding initiative.
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She added that environment chemical exposures, parental or lifestyle factors, such as nutrition, pharmaceuticals, obesity, or birth factors, such as prematurity, could be areas of interest.
..... A large team at Case Western Reserve university submitted a proposal, currently under review, to analyze patient health records to search for common factors that may lead to autism.
..... Dr. David Kaelber, professor of pediatrics and population quantitative health sciences at the university, emphasized the importance of using real world data to address questions about autism, including potential links to vaccines and environmental factors.
..... Harvard, Columbia, Brigham, Stanford, and Johns Hopkins did not respond to Reuters request for comment.
..... Each project will undergo independent replication to help verify the reliability and reproducibility of new analyses, according to NIH's proposal.
..... One applicant, who submitted a proposal to study prenatal exposures that may cause autism, said he was impressed with the requirements to share data with a trusted partner for replication.
..... The applicant, who spoke anonymously to prevent jeopardizing the applications under consideration, said he "hoped that all HHS-sponsored autism studies would be subject to the same scrutiny."